Estimating Survival Data from Published Kaplan-Meier Curves: a Comparison of Methods
نویسندگان
چکیده
منابع مشابه
Enhanced secondary analysis of survival data: reconstructing the data from published Kaplan-Meier survival curves
BACKGROUND The results of Randomized Controlled Trials (RCTs) on time-to-event outcomes that are usually reported are median time to events and Cox Hazard Ratio. These do not constitute the sufficient statistics required for meta-analysis or cost-effectiveness analysis, and their use in secondary analyses requires strong assumptions that may not have been adequately tested. In order to enhance ...
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BACKGROUND In general, the individual patient-level data (IPD) collected in clinical trials are not available to independent researchers to conduct economic evaluations; researchers only have access to published survival curves and summary statistics. Thus, methods that use published survival curves and summary statistics to reproduce statistics for economic evaluations are essential. Four meth...
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the 5-year survival rate is a good prognostic indicator for patients with gastric cancer that is usually estimated based on kaplan-meier. in situations where censored observations are too many, this method produces biased estimations. this study aimed to compare estimations of kaplan-meier and weighted kaplan-meier as an alternative method to deal with the problem of heavy-censoring. data from ...
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OBJECTIVES: HTA bodies increasingly require accurate survival estimates to provide reliable recommendations. It is argued that access to individual patient data (IPD) can improve their accuracy. This poster aims to assess to what degree extracting IPD from published Kaplan-Meier (KM) curves helps improve extrapolated survival estimates. Some methods currently used for HTA submissions fit a surv...
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The Kaplan-Meier (KM) method is used to analyze 'time-to-event' data. The outcome in KM analysis often includes all-cause mortality, but could also include other outcomes such as the occurrence of a cardiovascular event. The purpose of this article is to explain the basic concepts of the KM method, to provide some guidance regarding the presentation of the KM results and to discuss some importa...
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ژورنال
عنوان ژورنال: Value in Health
سال: 2014
ISSN: 1098-3015
DOI: 10.1016/j.jval.2014.08.588